Sept. 2009: Launch of ALEXA-Seq website. Go here to get started

Oct. 2009: Release of the ALEXA-Seq data viewer.

Nov. 2009: The first data set analyzed can be viewed here: 5-FU resistance in colorectal cancer.

Dec. 2009: Three additional data sets have been recently added and and four more are being processed. These include studies of: mouse liver development, Iressa and Sutent resistance in cancer, lymphoma, multiple myeloma, neuroblastoma, lung cancer, etc.

If you wish to jump straight to a summary of alternative expression results or search for a specific gene, click one of the buttons below.

We use the term 'ALEXA' to describe a collection of novel genomic methods for 'alternative expression' analysis. 'Alternative expression' refers to the identification and quantification of alternative mRNA transcripts produced by alternative transcript initiation, alternative splicing and alternative polyadenylation. This website provides supplementary materials, source code and other downloads for recent publications describing our studies of alternative expression.

This work was conducted at the Genome Sciences Centre a department of the British Columbia Cancer Agency.

The ALEXA website provides supplementary materials and downloads for manuscripts covering: an introduction to alternative expression (AE), analysis of AE by microarrays, analysis of AE by massively parallel RNA sequencing and the application of these methods to the study of drug resistance in cancer

Click on the appropriate tab to navigate to the supplementary materials for one or our studies. See the acknowledgements section for citations. See the contact section to contact us directly.